Rh-catalyzed decarbonylation of conjugated ynones via carbon–alkyne bond activation: reaction scope and mechanistic exploration via DFT calculations† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc00584a
نویسندگان
چکیده
In this full article, detailed development of a catalytic decarbonylation of conjugated monoynones to synthesize disubstituted alkynes is described. The reaction scope and limitation has been thoroughly investigated, and a broad range of functional groups including heterocycles were compatible under the catalytic conditions. Mechanistic exploration via DFT calculations has also been executed. Through the computational study, a proposed catalytic mechanism has been carefully evaluated. These efforts are expected to serve as an important exploratory study for developing catalytic alkyne-transfer reactions via carbon-alkyne bond activation.
منابع مشابه
Rh-catalyzed decarbonylation of conjugated ynones via carbon–alkyne bond activation: reaction scope and mechanistic exploration via DFT calculations
The University of Texas at Austin, Departm Beijing National Laboratory of Molecular Bioorganic Chemistry and Molecular Eng University, Beijing, 100871, China Key Laboratory of Pesticide & Chemical B Chemistry, Central China Normal Universit † Electronic supplementary informa 10.1039/c5sc00584a ‡ Current address: Pzer Inc., Eastern P States. § AD and REW contributed equally. Cite this: Chem. Sc...
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